METATIDE

a new generation of innovative peptide technology that could potentially benefit all cancer patients, regardless of the cellular marker, tumor site, and cancer stage ...

N1-109

Ovarian
Cancer &
Ovarian
Clear Cell
Carcinoma

N1-115

Brain
Cancer &
Brain
Metastasis

  • Metastasis and TME Targeting

    MetaTide carries payload drug to preferentially localize at tumor and tumor metastasis sites based on the peptide's unique interaction with tumor microenvironment factors and tumor surface factors

  • Tumor and Tissue Penetration

    MetaTide-drug conjugate (MDC) penetrats solid tumor to treat the unexposed tumor tissues and cells that are not susceptible to antibody-drug conjugates (ADCs), and biological therapeutics (i.e. PD1/PD-L1, mAbs)

  • Intracellular Delivery & Release

    MetaTide-drug conjugate (MDC) utilizes Absotride's proprietary linker designed to cleave and release active drug after an efficient intracellular delivery into cancer cells. The release is dependent on the biological stimuli of tumor cell cytosol environment

  • Overcoming Drug Resistance

    Metatide enables drug molecules to overcome drug resistance mediated by membrane-associated export pumps. The ability of MetaTide to overcome complex clinical multi-drug resistance has been approved in human tumors.