N1's oligomeric technology that enables tissue penetration and intracellular delivery of oligonucleotides for gene therapy
Penetide, a peptide-based transporter technology targeting tumor microenvironment, carries the drug and localizes at tumor and metastasis site by interacting with tumor microenvironment
Absotride's proprietary linker technology that is designed to cleave and release active parent drug after entering tumor cells. The release is dependent on the biological stimuli of intracellular and tumor microenvironment
Penetide enables the parent drug to overcome drug resistance mediated by membrane-associated export transporters, such as ATP-binding cassette (ABC) transporter P-glycoprotein (Pgp). Pgp is known to over-express in over 60% of cancers, particularly in peritoneal cancers and blood-brain barrier